Strategy Workshop
The Challenge: TherapeutAix was contacted by an institution wanting to define areas to build capabilities. Their goal was to better complement expertise and to meet unmet demand for its partners and prospective clients. The Action: We aligned with our client on the scope of work. Next, we organised a workshop to align on must-haves as […]
Advancing Assets
The Challenge: TherapeutAix was approached by a small biotech company that operated in a fully virtual setting. To progress assets on a novel drug delivery platform technology, the biotech asked for help in defining the required steps to take the lead asset to IND-enabling studies and in the clinic. The Action: A thorough literature review […]
First-in-Human Clinical Trials
The Challenge: TherapeutAix was contacted by an innovative biotech company that was undertaking final preparations for First-in-Human clinical trials. It was known that their biologic has a complex metabolic pathway in vivo. One of the bioanalytical methods needed a major overhaul to be on the same technical level as the rest of the analytical toolbox. […]
Asset for Fibrotic Disease
The Challenge: TherapeutAix was approached by a US-based biotech company to review an asset that they were considering repositioning for fibrotic disease. The company asked for specific help in reviewing existing data, defining the steps then required to take the asset to IND-enabling studies and into the clinic. The Action: The task was to review the […]
Target and Asset Review
The Challenge: TherapeutAix was approached by a small virtual biotech to review a target and asset that for a rare fibrotic disease. The company asked for specific help in reviewing the target, existing data, defining the steps then required to take the asset to IND and into the clinic. The task was to review the existing data and background information and to provide an […]
Translational Strategy
The Challenge: A small, highly virtualized biotech had identified an attractive target in fibrotic diseases and needed a translational strategy to generate clinical data that enables data-driven decision-making for future development as well as increases the asset value. The Action: TherapeutAix was contracted to define the translational approach scoping elements ranging from in vitro / in […]
Inhaled Drug Delivery to the Lung
The Challenge: TherapeutAix was approached by a small biotech company developing a device with the potential to enhance inhaled drug delivery to the lung. The company required guidance on the choice of indication and drug to provide proof of principle (PoP) for the enhanced delivery. We were requested to scan the existing inhaled drug landscape and provide recommendations […]